Here is a collection of the most frequently asked questions we receive about SteroidPlotter.com:
- Q: Why do the charts look different from the previous version/other plotter sites?
- A: The application has been rebuilt to provide a more accurate visible representation of the pharmacokinetics of the included compounds.
- Q: The elimination half-life of Drug X is Y days. Why isn’t the level at 50% by day Y?
- A: The plotter now accounts for the time to peak value (Tmax). The elimination half-life only begins once peak levels are reached. Other plotters and the previous version of our application, which show the levels to rise instantly to peak, do not accurately reflect the pharmacokinetics of the compound.
- Q: There is a compound I’d love to see added to the plotter. How can I get it added?
- A: Drop us a message or join our Telegram group to let us know, and we’ll get it added. If you can provide peer-reviewed studies showing the following data, this will speed up the process:
- t1/2 (half-life)
- Cmax (peak concentration)
- Tmax (time at which Cmax is observed)
- F(%) (bioavailability)
- Q: Will the plotter accurately represent the levels of each compound in my blood?
- A: No, studies show vastly differing pharmacokinetics among individuals due to factors such as metabolism, body composition, age, and genetic variances. We cannot account for all individual differences. We also used simplified models, which do not reflect real-world values. The calculated levels are estimates based on generalized information and should not be considered precise.
- Q: How often is the database of compounds updated?
- A: The database is updated either when a user requests a new compound to be added or if we are pointed to higher-quality sources for pharmacokinetic data for a particular compound.
- Q: Can I compare multiple dosing protocols of the same compound?
- A: Yes. You can set the switch under each compound to “Compare,” allowing you to see multiple protocols for the same compound on the chart.
- Q: Why do the values peak higher for longer esters than short esters? Does this mean my blood levels will be lower with a shorter ester?
- A: Shorter esters are cleared more quickly than longer esters due to shorter half-lives and sometimes time to peak values. This means that accumulation leads to a lower steady state even when the exact same dosage is used. Therefore, levels of Deca, for example, compared to NPP, will be much higher at the same weekly dosage once a steady state is reached.